HOX13-dependent chromatin accessibility underlies the transition towards the digit development program

Hox genes encode transcription factors (TFs) that establish morphological diversity in the developing embryo. The similar DNA-binding motifs of the various HOX TFs contrast with the wide-range of HOX-dependent genetic programs. The influence of the chromatin context on HOX binding specificity remain...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Desanlis, Ines, Kherdjemil, Yacine, Mayran, Alexandre, Bouklouch, Yasser, Gentile, Claudia, Sheth, Rushikesh, Zeller, Rolf, Drouin, Jacques, Kmita, Marie
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237422/
https://ncbi.nlm.nih.gov/pubmed/32427842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16317-2
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