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Let-7 microRNA is a critical regulator in controlling the growth and function of silk gland in the silkworm

The silk gland is characterized by high protein synthesis. However, the molecular mechanisms controlling silk gland growth and silk protein synthesis remain undetermined. Here we demonstrated that CRISPR/Cas9-based knockdown of let-7 or the whole cluster promoted endoreduplication and enlargement of...

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Détails bibliographiques
Publié dans:RNA Biol
Auteurs principaux: Wang, Wei, Wang, Xinran, Luo, Chengyi, Pu, Qian, Yin, Quan, Xu, Lili, Peng, Xinyue, Ma, Sanyuan, Xia, Qingyou, Liu, Shiping
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237193/
https://ncbi.nlm.nih.gov/pubmed/32019402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1726128
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