Regulating polymyxin resistance in Gram-negative bacteria: roles of two-component systems PhoPQ and PmrAB

Polymyxins (polymyxin B and colistin) are last-line antibiotics against multidrug-resistant Gram-negative pathogens. Polymyxin resistance is increasing worldwide, with resistance most commonly regulated by two-component systems such as PmrAB and PhoPQ. This review discusses the regulatory mechanisms...

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Detalles Bibliográficos
Publicado en:Future Microbiol
Main Authors: Huang, Jiayuan, Li, Chen, Song, Jiangning, Velkov, Tony, Wang, Lushan, Zhu, Yan, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado: Future Medicine Ltd 2020
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236789/
https://ncbi.nlm.nih.gov/pubmed/32250173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb-2019-0322
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