Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer

BACKGROUND: While combinations of immune checkpoint (ICP) inhibitors and neo-adjuvant chemotherapy (NAC) have begun testing in patients with breast cancer (BC), the effects of chemotherapy on ICP expression in circulating T cells and within the tumor microenvironment are still unclear. This informat...

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Udgivet i:BMC Cancer
Main Authors: Wesolowski, Robert, Stiff, Andrew, Quiroga, Dionisia, McQuinn, Christopher, Li, Zaibo, Nitta, Hiroaki, Savardekar, Himanshu, Benner, Brooke, Ramaswamy, Bhuvaneswari, Lustberg, Maryam, Layman, Rachel M., Macrae, Erin, Kassem, Mahmoud, Williams, Nicole, Sardesai, Sagar, VanDeusen, Jeffrey, Stover, Daniel, Cherian, Mathew, Mace, Thomas A., Yu, Lianbo, Duggan, Megan, Carson, William E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236344/
https://ncbi.nlm.nih.gov/pubmed/32429929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06949-4
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