DPD status and fluoropyrimidines-based treatment: high activity matters too

BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) status is an indicator of a marked risk for toxicity following fluoropyrimidine (FP)-based chemotherapy. This notion is well-established for low DPD status but little is known about the clinical impact of high DPD activity. This study examined the po...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Chamorey, Emmanuel, Francois, Eric, Etienne, Marie-Christine, Ferrero, Jean-Marc, Peyrade, Frederic, Barranger, Emmanuel, Bozec, Alexandre, Largillier, Rémy, Cassuto, Ophelie, Viotti, Julien, Schiappa, Renaud, Milano, Gérard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236295/
https://ncbi.nlm.nih.gov/pubmed/32423482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06907-0
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