Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy

Microglia are resident macrophages of the central nervous system, and their unique molecular signature is dependent upon CSF-1 signaling. Previous studies have demonstrated the importance of CSF-1R in survival and development of microglia in animal models, but the findings are of uncertain relevance...

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Podrobná bibliografie
Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Kempthorne, Liam, Yoon, Hyejin, Madore, Charlotte, Smith, Scott, Wszolek, Zbigniew K., Rademakers, Rosa, Kim, Jungsu, Butovsky, Oleg, Dickson, Dennis W.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236286/
https://ncbi.nlm.nih.gov/pubmed/32430064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00947-0
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