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Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors

[Image: see text] The synthesis of selective inhibitors of human carbonic anhydrases (hCAs) is of paramount importance to avoid side effects derived from undesired interactions with isoforms not involved in the targeted pathology, and this was partially addressed with the introduction of a sugar moi...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Pratesi, Debora, Matassini, Camilla, Goti, Andrea, Angeli, Andrea, Carta, Fabrizio, Supuran, Claudiu T., Spanevello, Rolando, Cardona, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236246/
https://ncbi.nlm.nih.gov/pubmed/32435377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00590
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