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Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis

BACKGROUND: Amplification of chromosome 7q21-7q31 is associated with tumor recurrence and multidrug resistance, and several genes in this region are powerful drivers of hepatocellular carcinoma (HCC). We aimed to investigate the key circular RNAs (circRNAs) in this region that regulate the initiatio...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Huang, Xiao-Yong, Zhang, Peng-Fei, Wei, Chuan-Yuan, Peng, Rui, Lu, Jia-Cheng, Gao, Chao, Cai, Jia-Bing, Yang, Xuan, Fan, Jia, Ke, Ai-Wu, Zhou, Jian, Shi, Guo-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236145/
https://ncbi.nlm.nih.gov/pubmed/32430013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01213-6
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