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Lipid droplet assembly factor-1 and seipin form a lipid droplet assembly complex

Lipid droplets (LDs) originate from the endoplasmic reticulum (ER) to store triacylglycerol (TG) and cholesterol esters. The ER protein seipin was shown to localize to ER-LD contacts soon after LDs form, but what determines the sites of initial LD biogenesis in the ER is unknown. Here we identify TM...

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Bibliografske podrobnosti
izdano v:Dev Cell
Main Authors: Chung, Jeeyun, Wu, Xudong, Lambert, Talley J., Lai, Zon Weng, Walther, Tobias C., Farese, Robert V.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235935/
https://ncbi.nlm.nih.gov/pubmed/31708432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.10.006
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