PP1C and PP2A are p70S6K Phosphatases Whose Inhibition Ameliorates HLD12-Associated Inhibition of Oligodendroglial Cell Morphological Differentiation

Myelin sheaths created by oligodendroglial cells encase neuronal axons to achieve saltatory conduction and protect axons. Pelizaeus-Merzbacher disease (PMD) is a prototypic, hereditary demyelinating oligodendroglial disease of the central nervous system (CNS), and is currently known as hypomyelinati...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Matsumoto, Naoto, Miyamoto, Yuki, Hattori, Kohei, Ito, Akihiro, Harada, Hironori, Oizumi, Hiroaki, Ohbuchi, Katsuya, Mizoguchi, Kazushige, Yamauchi, Junji
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235839/
https://ncbi.nlm.nih.gov/pubmed/32316234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8040089
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