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Pharmacokinetics of Macrolide Antibiotics and Transport into the Interstitial Fluid: Comparison among Erythromycin, Clarithromycin, and Azithromycin

Recent research has found higher levels and longer total exposure of azithromycin, a macrolide antibiotic agent, in the interstitial fluid of the skin than in the plasma. This unique distribution is expected to contribute to its antimicrobial activity at the primary infection site. However, it remai...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Kobuchi, Shinji, Kabata, Teruhiko, Maeda, Koki, Ito, Yukako, Sakaeda, Toshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235806/
https://ncbi.nlm.nih.gov/pubmed/32331283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9040199
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