CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract

Characteristic of allergic asthma, CD4+Th2 lymphocytes secrete Th2 cytokines, interleukin (IL)-4, IL-13, and IL-5 that mediate the inflammatory immune response. Surface expression of CD2 and its ligand, CD58, is increased on the monocytes and eosinophils of asthma patients, which correlate with elev...

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Pubblicato in:Front Immunol
Autori principali: Hashem, Tanwir, Kammala, Ananth K., Thaxton, Kanedra, Griffin, Ryan M., Mullany, Kellie, Panettieri, Reynold A., Subramanian, Hariharan, Das, Rupali
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235426/
https://ncbi.nlm.nih.gov/pubmed/32477356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00881
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