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Identifying inhibitors of epithelial–mesenchymal plasticity using a network topology-based approach

Metastasis is the cause of over 90% of cancer-related deaths. Cancer cells undergoing metastasis can switch dynamically between different phenotypes, enabling them to adapt to harsh challenges, such as overcoming anoikis and evading immune response. This ability, known as phenotypic plasticity, is c...

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Detalles Bibliográficos
Publicado en:NPJ Syst Biol Appl
Main Authors: Hari, Kishore, Sabuwala, Burhanuddin, Subramani, Balaram Vishnu, La Porta, Caterina A. M., Zapperi, Stefano, Font-Clos, Francesc, Jolly, Mohit Kumar
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235229/
https://ncbi.nlm.nih.gov/pubmed/32424264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-020-0132-1
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