Characterization and strong risk association of TLR2 del -196 to -174 polymorphism and Helicobacter pylori and their influence on mRNA expression in gastric cancer

BACKGROUND: Toll-like receptor-2 (TLR2) is responsible for recognizing Helicobacter pylori (H. pylori) and activating the immune response. Polymorphisms in TLR2 may modulate gastric carcinogenesis. AIM: To evaluate whether the TLR2 19216T/C (rs3804099) and TLR2 -196 to -174 ins/del (rs111200466) pol...

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Detalhes bibliográficos
Publicado no:World J Gastrointest Oncol
Main Authors: Lourenço, Caroline de Matos, Susi, Manoela Dias, do Nascimento, Mariah Cristina Antunes, Serafim Junior, Vilson, Vila, Ana Paula Simedan, Rodrigues-Flemming, Gabriela Helena, Goloni-Bertollo, Eny Maria, Silva, Ana Elizabete, de Oliveira-Cucolo, Juliana Garcia
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2020
Assuntos:
Case Control Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235183/
https://ncbi.nlm.nih.gov/pubmed/32461785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v12.i5.535
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