Mycobacterium tuberculosis Infection-Driven Foamy Macrophages and Their Implications in Tuberculosis Control as Targets for Host-Directed Therapy

Tuberculosis (TB) is a leading cause of death worldwide following infection with Mycobacterium tuberculosis (Mtb), with 1.5 million deaths from this disease reported in 2018. Once the bacilli are inhaled, alveolar and interstitial macrophages become infected with Mtb and differentiate into lipid-lad...

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Udgivet i:Front Immunol
Main Authors: Shim, Dahee, Kim, Hagyu, Shin, Sung Jae
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235167/
https://ncbi.nlm.nih.gov/pubmed/32477367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00910
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