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M204. ULTRA-RESISTANT SCHIZOPHRENIA IS ASSOCIATED WITH A DELAY TO INITIATE CLOZAPINE AND WITH LESS ABDOMINAL OBESITY. SEX DIFFERENCES IN INSULINEMIA AND LEPTIN LEVELS ARE OBSERVED BETWEEN RESPONDERS AND NOT RESPONDERS

BACKGROUND: 30% patients suffering from schizophrenia fail to obtain therapeutic benefit even after two appropriate antipsychotic trials and are considered resistant. The recommended treatment in these cases is clozapine (CLZ), but only 40% of patients with resistant schizophrenia show clinical resp...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Hönig, Guillermo, Rodante, Demián, Daray, Federico, Izaguirre, Mercedes, Lenze, Mariela, Valentini, Joaquín, García Bournissen, Facundo, Laura Gutiérrez, María, Wikinski, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7234559/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbaa030.516
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