The perceived impact of isoniazid resistance on outcome of first-line rifampicin-throughout regimens is largely due to missed rifampicin resistance

BACKGROUND: Meta-analyses on impact of isoniazid-resistant tuberculosis informed the World Health Organization recommendation of a levofloxacin-strengthened rifampicin-based regimen. We estimated the effect of initial rifampicin resistance (Rr) and/or isoniazid resistance (Hr) on treatment failure o...

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Udgivet i:PLoS One
Main Authors: Van Deun, Armand, Decroo, Tom, Kya Jai Maug, Aung, Hossain, Mohamed Anwar, Gumusboga, Murid, Mulders, Wim, Ortuño-Gutiérrez, Nimer, Lynen, Lutgarde, de Jong, Bouke C., Rieder, Hans L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233532/
https://ncbi.nlm.nih.gov/pubmed/32421749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233500
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