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Cystic Fibrosis: Emergence of Highly Effective Targeted Therapeutics and Potential Clinical Implications

Cystic fibrosis (CF) remains the most common life-shortening hereditary disease in white populations, with high morbidity and mortality related to chronic airway mucus obstruction, inflammation, infection, and progressive lung damage. In 1989, the discovery that CF is caused by mutations in the CFTR...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Mall, Marcus A., Mayer-Hamblett, Nicole, Rowe, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233349/
https://ncbi.nlm.nih.gov/pubmed/31860331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201910-1943SO
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