Biochemical and molecular aspects of 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis: a review

1,2-dimethylhydrazine (DMH) is a member in the class of hydrazines, strong DNA alkylating agent, naturally present in cycads. DMH is widely used as a carcinogen to induce colon cancer in animal models. Exploration of DMH-induced colon carcinogenesis in rodent models provides the knowledge to perceiv...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Venkatachalam, Karthikkumar, Vinayagam, Ramachandran, Arokia Vijaya Anand, Mariadoss, Isa, Nurulfiza Mat, Ponnaiyan, Rajasekar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233314/
https://ncbi.nlm.nih.gov/pubmed/32440334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxres/tfaa004
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