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Mitochondria Biogenesis Modulates Iron–Sulfur Cluster Synthesis to Increase Cellular Iron Uptake

Iron–sulfur (Fe-S) clusters are required for mitochondrial function. Fe-S cluster synthesis occurs in the mitochondria and iron uptake is required for mitochondrial biogenesis. However, Fe-S clusters inhibit the expression of the iron importer transferrin receptor 1 (TfR1), whereas lack of the Fe-S...

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Pubblicato in:DNA Cell Biol
Autori principali: La, Ping, Oved, Joseph H., Ghiaccio, Valentina, Rivella, Stefano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232706/
https://ncbi.nlm.nih.gov/pubmed/32282232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2019.5123
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