Heme Oxygenase-1 Is a Pivotal Modulator of Bone Turnover and Remodeling: Molecular Implications for Prostate Cancer Bone Metastasis

Aims: Bone is the most frequent site of prostate cancer (PCa) metastasis. Tumor cells interact with the bone microenvironment interrupting tissue balance. Heme oxygenase-1 (HO-1; encoded by Hmox1) appears as a potential target in PCa maintaining the cellular homeostasis. Our hypothesis is that HO-1...

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Опубликовано в: :Antioxid Redox Signal
Главные авторы: Anselmino, Nicolás, Starbuck, Michael, Labanca, Estefania, Cotignola, Javier, Navone, Nora, Gueron, Geraldine, Zenclussen, Ana C., Vazquez, Elba
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc., publishers 2020
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Forum Original Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232646/
https://ncbi.nlm.nih.gov/pubmed/31861963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2019.7879
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