Scald Injury-Induced T Cell Dysfunction Can Be Mitigated by Gr1(+) Cell Depletion and Blockage of CD47/CD172a Signaling

Infection is a common and severe complication of burn injury: Sepsis accounts for 47% of postburn mortality. Burn-induced T cell suppression likely contributes to the increased infection susceptibility in burn patients. However, little is known about the kinetics of T cell dysfunction after burn and...

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Udgivet i:Front Immunol
Main Authors: Beckmann, Nadine, Huber, Franziska, Hanschen, Marc, St. Pierre Schneider, Barbara, Nomellini, Vanessa, Caldwell, Charles C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232553/
https://ncbi.nlm.nih.gov/pubmed/32477354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00876
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