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Targeting the SAGA and ATAC transcriptional coactivator complexes in MYC-driven cancers

Targeting epigenetic regulators such as histone modifying enzymes provides novel strategies for cancer therapy. The GCN5 lysine acetyltransferase (KAT) functions together with MYC both during normal development and in oncogenesis. As transcription factors, MYC family members are difficult to target...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Mustachio, Lisa Maria, Roszik, Jason, Farria, Aimee, Dent, Sharon Y.R.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231639/
https://ncbi.nlm.nih.gov/pubmed/32094302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3652
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