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Targeting the SAGA and ATAC transcriptional coactivator complexes in MYC-driven cancers
Targeting epigenetic regulators such as histone modifying enzymes provides novel strategies for cancer therapy. The GCN5 lysine acetyltransferase (KAT) functions together with MYC both during normal development and in oncogenesis. As transcription factors, MYC family members are difficult to target...
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| Publicado en: | Cancer Res |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7231639/ https://ncbi.nlm.nih.gov/pubmed/32094302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3652 |
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