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Targeting the SAGA and ATAC transcriptional coactivator complexes in MYC-driven cancers

Targeting epigenetic regulators such as histone modifying enzymes provides novel strategies for cancer therapy. The GCN5 lysine acetyltransferase (KAT) functions together with MYC both during normal development and in oncogenesis. As transcription factors, MYC family members are difficult to target...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Mustachio, Lisa Maria, Roszik, Jason, Farria, Aimee, Dent, Sharon Y.R.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231639/
https://ncbi.nlm.nih.gov/pubmed/32094302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3652
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