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Metabolic Switching of Tumor Cells under Hypoxic Conditions in a Tumor-on-a-chip Model

Hypoxia switches the metabolism of tumor cells and induces drug resistance. Currently, no therapeutic exists that effectively and specifically targets hypoxic cells in tumors. Development of such therapeutics critically depends on the availability of in vitro models that accurately recapitulate hypo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Micromachines (Basel)
Prif Awduron: Palacio-Castañeda, Valentina, Kooijman, Lucas, Venzac, Bastien, Verdurmen, Wouter P.R., Le Gac, Séverine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231186/
https://ncbi.nlm.nih.gov/pubmed/32260396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/mi11040382
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