Concomitant TP53 Mutation Confers Worse Prognosis in EGFR-Mutated Non-Small Cell Lung Cancer Patients Treated with TKIs

Background: Non-small cell lung cancer (NSCLC) is the primary cause of cancer-related deaths worldwide. Epidermal Growth Factor Receptor (EGFR)-mutated patients usually benefit from TKIs treatment, but a significant portion show unresponsiveness due to primary resistance mechanisms. We investigated...

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Bibliografiske detaljer
Udgivet i:J Clin Med
Main Authors: Canale, Matteo, Petracci, Elisabetta, Delmonte, Angelo, Bronte, Giuseppe, Chiadini, Elisa, Ludovini, Vienna, Dubini, Alessandra, Papi, Maximilian, Baglivo, Sara, De Luigi, Nicoletta, Verlicchi, Alberto, Chiari, Rita, Landi, Lorenza, Metro, Giulio, Burgio, Marco Angelo, Crinò, Lucio, Ulivi, Paola
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230306/
https://ncbi.nlm.nih.gov/pubmed/32272775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9041047
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