Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress

A key reason for the persistently grim statistics associated with metastatic ovarian cancer is resistance to conventional agents, including platinum-based chemotherapies. A major source of treatment failure is the high degree of genetic and molecular heterogeneity, which results from significant und...

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Publicado no:J Clin Med
Main Authors: Nath, Shubhankar, Pigula, Michael, Khan, Amjad P., Hanna, William, Ruhi, Mustafa Kemal, Dehkordy, Farzaneh Mahmoodpoor, Pushpavanam, Karthik, Rege, Kaushal, Moore, Kaitlin, Tsujita, Yujiro, Conrad, Christina, Inci, Fatih, del Carmen, Marcela G., Franco, Walfre, Celli, Jonathan P., Demirci, Utkan, Hasan, Tayyaba, Huang, Huang-Chiao, Rizvi, Imran
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230263/
https://ncbi.nlm.nih.gov/pubmed/32231055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9040924
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