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The Kinetic and Molecular Basis for the Interaction of LexA and Activated RecA Revealed by a Fluorescent Amino Acid Probe

The bacterial DNA damage response (the SOS response) is a key pathway involved in antibiotic evasion and a promising target for combating acquired antibiotic resistance. Activation of the SOS response is controlled by two proteins: the repressor LexA and the DNA damage sensor RecA. Following DNA dam...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Hostetler, Zachary M., Cory, Michael B., Jones, Chloe M., Petersson, E. James, Kohli, Rahul M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230020/
https://ncbi.nlm.nih.gov/pubmed/31999086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00886
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