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Small circRNAs with self-cleaving ribozymes are highly expressed in diverse metazoan transcriptomes

Ribozymes are catalytic RNAs present in modern genomes but regarded as remnants of a prebiotic RNA world. The paradigmatic hammerhead ribozyme (HHR) is a small self-cleaving motif widespread from bacterial to human genomes. Here, we report that most of the classical type I HHRs frequently found in t...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Cervera, Amelia, de la Peña, Marcos
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229834/
https://ncbi.nlm.nih.gov/pubmed/32198887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa187
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