A non-canonical promoter element drives spurious transcription of horizontally acquired bacterial genes

RNA polymerases initiate transcription at DNA sequences called promoters. In bacteria, the best conserved promoter feature is the AT-rich -10 element; a sequence essential for DNA unwinding. Further elements, and gene regulatory proteins, are needed to recruit RNA polymerase to the -10 sequence. Hen...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Warman, Emily A, Singh, Shivani S, Gubieda, Alicia G, Grainger, David C
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229825/
https://ncbi.nlm.nih.gov/pubmed/32297955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa244
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