Pranlukast Antagonizes CD49f and Reduces Stemness in Triple-Negative Breast Cancer Cells

INTRODUCTION: Cancer stem cells (CSCs) drive the initiation, maintenance, and therapy response of breast tumors. CD49f is expressed in breast CSCs and functions in the maintenance of stemness. Thus, blockade of CD49f is a potential therapeutic approach for targeting breast CSCs. In the present stu...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Velázquez-Quesada, Inés, Ruiz-Moreno, Angel J, Casique-Aguirre, Diana, Aguirre-Alvarado, Charmina, Cortés-Mendoza, Fabiola, de la Fuente-Granada, Marisol, García-Pérez, Carlos, Pérez-Tapia, Sonia M, González-Arenas, Aliesha, Segura-Cabrera, Aldo, Velasco-Velázquez, Marco A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229803/
https://ncbi.nlm.nih.gov/pubmed/32494122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S247730
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