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The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage

Lipases are enzymes necessary for the proper distribution and utilization of lipids in the human body. Lipoprotein lipase (LPL) is active in capillaries, where it plays a crucial role in preventing dyslipidemia by hydrolyzing triglycerides from packaged lipoproteins. Thirty years ago, the existence...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gunn, Kathryn H., Roberts, Benjamin S., Wang, Fengbin, Strauss, Joshua D., Borgnia, Mario J., Egelman, Edward H., Neher, Saskia B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229681/
https://ncbi.nlm.nih.gov/pubmed/32332168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916555117
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