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Loss of Arc attenuates the behavioral and molecular responses for sleep homeostasis in mice

The activity-regulated cytoskeleton-associated protein (Arc) gene is a neural immediate early gene that is involved in synaptic downscaling and is robustly induced by prolonged wakefulness in rodent brains. Converging evidence has led to the hypothesis that wakefulness potentiates, and sleep reduces...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Suzuki, Ayako, Yanagisawa, Masashi, Greene, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229651/
https://ncbi.nlm.nih.gov/pubmed/32350140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906840117
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