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Methylation Analysis of P16, RASSF1A, RPRM, and RUNX3 in Circulating Cell-Free DNA for Detection of Gastric Cancer: A Validation Study

BACKGROUND: Most of Gastric Cancer (GC) patients are diagnosed at an advanced stage with poor prognosis. Hypermethylations of several tumor suppressor genes in cell-free DNA of GC patients have been previously reported. In this study, an attempt was made to investigate the methylation status of P16,...

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Veröffentlicht in:Avicenna J Med Biotechnol
Hauptverfasser: Saliminejad, Kioomars, Soleymani Fard, Shahrzad, Khorram Khorshid, Hamid Reza, Yaghmaie, Marjan, Mahmoodzadeh, Habibollah, Mousavi, Seyed Asadollah, Ghaffari, Seyed Hamidollah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Avicenna Research Institute 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229449/
https://ncbi.nlm.nih.gov/pubmed/32431794
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