Spatial immune profiling of the colorectal tumor microenvironment predicts good outcome in stage II patients

Cellular subpopulations within the colorectal tumor microenvironment (TME) include CD3(+) and CD8(+) lymphocytes, CD68(+) and CD163(+) macrophages, and tumor buds (TBs), all of which have known prognostic significance in stage II colorectal cancer. However, the prognostic relevance of their spatial...

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Publicat a:NPJ Digit Med
Autors principals: Nearchou, Ines P., Gwyther, Bethany M., Georgiakakis, Elena C. T., Gavriel, Christos G., Lillard, Kate, Kajiwara, Yoshiki, Ueno, Hideki, Harrison, David J., Caie, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229187/
https://ncbi.nlm.nih.gov/pubmed/32435699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41746-020-0275-x
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