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Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection

BACKGROUND: Natural killer (NK) cells localize in the microcirculation in antibody-mediated rejection (AMR) and have been postulated to be activated by donor-specific anti-HLA antibodies triggering their CD16a Fc receptors. However, direct evidence for NK cell CD16a triggering in AMR is lacking. We...

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Bibliographische Detailangaben
Veröffentlicht in:Transplantation
Hauptverfasser: Parkes, Michael D., Halloran, Philip F., Hidalgo, Luis G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228621/
https://ncbi.nlm.nih.gov/pubmed/27906829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001586
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