Impact of a preceding radiotherapy on the outcome of immune checkpoint inhibition in metastatic melanoma: a multicenter retrospective cohort study of the DeCOG

BACKGROUND: Immune checkpoint inhibition (ICI) is an essential treatment option in melanoma. Its outcome may be improved by a preceding radiation of metastases. This study aimed to investigate the impact of a preceding radiotherapy on the clinical outcome of ICI treatment. METHODS: This multicenter...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Knispel, Sarah, Stang, Andreas, Zimmer, Lisa, Lax, Hildegard, Gutzmer, Ralf, Heinzerling, Lucie, Weishaupt, Carsten, Pföhler, Claudia, Gesierich, Anja, Herbst, Rudolf, Kaehler, Katharina C, Weide, Benjamin, Berking, Carola, Loquai, Carmen, Utikal, Jochen, Terheyden, Patrick, Kaatz, Martin, Schlaak, Max, Kreuter, Alexander, Ulrich, Jens, Mohr, Peter, Dippel, Edgar, Livingstone, Elisabeth, Becker, Jürgen C, Weichenthal, Michael, Chorti, Eleftheria, Gronewold, Janine, Schadendorf, Dirk, Ugurel, Selma
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Clinical/Translational Cancer Immunotherapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228559/
https://ncbi.nlm.nih.gov/pubmed/32371460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000395
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