SIRT1-dependent mechanisms and effects of resveratrol for amelioration of muscle wasting in NASH mice

BACKGROUND: In non-alcoholic steatohepatitis (NASH), muscle wasting was an aggravating factor for the progression of hepatic steatosis. This study explores the potential benefits of chronic treatment with resveratrol, a strong activator of SIRT1 on the muscle wasting of NASH mice. METHODS: In vivo a...

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Detalhes bibliográficos
Publicado no:BMJ Open Gastroenterol
Main Authors: Liu, Chih-Wei, Huang, Chia-Chang, Hsu, Chien-Fu, Li, Tzu-Hao, Tsai, Yu-Lien, Lin, Ming-Wei, Tsai, Hung-Cheng, Huang, Shiang-Fen, Yang, Ying-Ying, Hsieh, Yun-Cheng, Lee, Tzung-Yan, Tsai, Chang-Youh, Huang, Yi-Hsiang, Hou, Ming-Chih, Lin, Han-Chieh
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228468/
https://ncbi.nlm.nih.gov/pubmed/32371503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjgast-2020-000381
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