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The sensitivity of transcriptomics BMD modeling to the methods used for microarray data normalization
Whole-genome expression data generated by microarray studies have shown promise for quantitative human health risk assessment. While numerous approaches have been developed to determine benchmark doses (BMDs) from probeset-level dose responses, sensitivity of the results to methods used for normaliz...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7228135/ https://ncbi.nlm.nih.gov/pubmed/32413060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232955 |
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