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Design of composite measure schemes for comparative severity assessment in animal-based neuroscience research: A case study focussed on rat epilepsy models

Comparative severity assessment of animal models and experimental interventions is of utmost relevance for harm-benefit analysis during ethical evaluation, an animal welfare-based model prioritization as well as the validation of refinement measures. Unfortunately, there is a lack of evidence-based...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van Dijk, Roelof Maarten, Koska, Ines, Bleich, Andre, Tolba, Rene, Seiffert, Isabel, Möller, Christina, Di Liberto, Valentina, Talbot, Steven Roger, Potschka, Heidrun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228039/
https://ncbi.nlm.nih.gov/pubmed/32413036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230141
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