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Activation of meiotic genes mediates ploidy reduction during cryptococcal infection

Cryptococcus neoformans is a global human fungal pathogen that causes fatal meningoencephalitis in mostly immunocompromised individuals. During pulmonary infection, cryptococcal cells form large polyploid cells that exhibit increased resistance to host immune attack and are proposed to contribute to...

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Udgivet i:Curr Biol
Main Authors: Zhao, Youbao, Wang, Yina, Upadhyay, Srijana, Xue, Chaoyang, Lin, Xiaorong
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228024/
https://ncbi.nlm.nih.gov/pubmed/32109388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.01.081
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