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Diurnal control of blood pressure is uncoupled from sodium excretion

The diurnal rhythms of sodium handling and blood pressure are thought to be regulated by clock genes, such as Bmal1. However, little is known about the regulation of these factors by Bmal1, especially in rats. Using a novel whole-body Bmal1 knockout rat model (Bmal1(−/−)), we hypothesized that time...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Johnston, Jermaine G., Speed, Joshua S., Becker, Bryan K., Kasztan, Malgorzata, Soliman, Reham H., Rhoads, Megan K., Tao, Binli, Jin, Chunhua, Geurts, Aron M., Hyndman, Kelly A., Pollock, Jennifer S., Pollock, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228023/
https://ncbi.nlm.nih.gov/pubmed/32306766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13908
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