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Spatiotemporal Mislocalization of Nuclear Membrane-Associated Proteins in γ-Irradiation-Induced Senescent Cells

Cellular senescence, induced by genotoxic or replication stress, is accompanied by defects in nuclear morphology and nuclear membrane-heterochromatin disruption. In this work, we analyzed cytological and molecular changes in the linker of nucleoskeleton and cytoskeleton (LINC) complex proteins in se...

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Bibliographic Details
Published in:Cells
Main Authors: Alena, Svobodová Kovaříková, Eva, Bártová, Aleš, Kovařík, Emilie, Lukášová
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227243/
https://ncbi.nlm.nih.gov/pubmed/32316379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040999
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