Tumor-Intrinsic or Drug-Induced Immunogenicity Dictates the Therapeutic Success of the PD1/PDL Axis Blockade

Immunotherapy with immune checkpoint inhibitors (ICIs) has revolutionized cancer treatment providing unprecedented clinical benefits. However, many patients do not respond to ICIs as monotherapy or develop resistance. Combining ICI-based immunotherapy with chemotherapy is a promising strategy to inc...

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發表在:Cells
Main Authors: Rossi, Alessandra, Lucarini, Valeria, Macchia, Iole, Sestili, Paola, Buccione, Carla, Donati, Simona, Ciccolella, Maria, Sistigu, Antonella, D’Urso, Maria Teresa, Pacca, Anna Maria, Cardarelli, Enrico, Mattei, Fabrizio, Proietti, Enrico, Schiavoni, Giovanna, Bracci, Laura
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226952/
https://ncbi.nlm.nih.gov/pubmed/32290265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040940
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