SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction

Background: Aging is characterized by adipose tissue senescence, inflammation, and fibrosis, with trunk fat accumulation. Aging HIV-infected patients have a higher risk of trunk fat accumulation than uninfected individuals—suggesting that viral infection has a role in adipose tissue aging. We previo...

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Vydáno v:Cells
Hlavní autoři: Gorwood, Jennifer, Ejlalmanesh, Tina, Bourgeois, Christine, Mantecon, Matthieu, Rose, Cindy, Atlan, Michael, Desjardins, Delphine, Le Grand, Roger, Fève, Bruno, Lambotte, Olivier, Capeau, Jacqueline, Béréziat, Véronique, Lagathu, Claire
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226797/
https://ncbi.nlm.nih.gov/pubmed/32244726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040854
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