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Impaired Metabolic Flexibility in the Osteoarthritis Process: A Study on Transmitochondrial Cybrids

Osteoarthritis (OA) is the most frequent joint disease; however, the etiopathogenesis is still unclear. Chondrocytes rely primarily on glycolysis to meet cellular energy demand, but studies implicate impaired mitochondrial function in OA pathogenesis. The relationship between mitochondrial dysfuncti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Dalmao-Fernández, Andrea, Lund, Jenny, Hermida-Gómez, Tamara, Vazquez-Mosquera, María E, Rego-Pérez, Ignacio, Blanco, Francisco J., Fernández-Moreno, Mercedes
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226768/
https://ncbi.nlm.nih.gov/pubmed/32230786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040809
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