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Lamin Mutations Cause Increased YAP Nuclear Entry in Muscle Stem Cells

Mutations in the LMNA gene, encoding the nuclear envelope A-type lamins, are responsible for muscular dystrophies, the most severe form being the LMNA-related congenital muscular dystrophy (L-CMD), with severe defects in myonucleus integrity. We previously reported that L-CMD mutations compromise th...

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Pubblicato in:Cells
Autori principali: Owens, Daniel J., Fischer, Martina, Jabre, Saline, Moog, Sophie, Mamchaoui, Kamel, Butler-Browne, Gillian, Coirault, Catherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226749/
https://ncbi.nlm.nih.gov/pubmed/32231000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040816
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