Analysis of BRCA1 and RAD51C Promoter Methylation in Italian Families at High-Risk of Breast and Ovarian Cancer

Previous studies on breast and ovarian carcinoma (BC and OC) revealed constitutional BRCA1 and RAD51C promoter hypermethylation as epigenetic alterations leading to tumor predisposition. Nevertheless, the impact of epimutations at these genes is still debated. One hundred and eight women affected by...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Tabano, Silvia, Azzollini, Jacopo, Pesenti, Chiara, Lovati, Sara, Costanza, Jole, Fontana, Laura, Peissel, Bernard, Miozzo, Monica, Manoukian, Siranoush
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226593/
https://ncbi.nlm.nih.gov/pubmed/32276467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040910
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