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Extreme Diversity of IgGs Against Histones, DNA, and Myelin Basic Protein in the Cerebrospinal Fluid and Blood of Patients with Multiple Sclerosis

It was recently shown that IgGs from sera of multiple sclerosis (MS) patients are active in the hydrolysis of DNA and myelin basic protein (MBP). We first analyzed the relative concentration of antibodies against five histones (H1, H2a, H2b, H3, and H4) in the cerebrospinal fluid (CSF) and serum of...

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Bibliografische gegevens
Gepubliceerd in:Biomolecules
Hoofdauteurs: Kostrikina, Irina A., Buneva, Valentina N., Granieri, Enrico, Nevinsky, Georgy A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226582/
https://ncbi.nlm.nih.gov/pubmed/32325782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040630
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