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The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in a Zebrafish Xenograft Colon Cancer Model

Malfunctions of circadian clock trigger abnormal cellular processes and influence tumorigenesis. Using an in vitro and in vivo xenograft model, we show that circadian clock disruption via the downregulation of the core-clock genes BMAL1, PER2, and NR1D1 impacts the circadian phenotype of MYC, WEE1,...

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Bibliografiset tiedot
Julkaisussa:Cancers (Basel)
Päätekijät: Basti, Alireza, Fior, Rita, Yalҫin, Müge, Póvoa, Vanda, Astaburuaga, Rosario, Li, Yin, Naderi, Julian, Godinho Ferreira, Miguel, Relógio, Angela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226575/
https://ncbi.nlm.nih.gov/pubmed/32244760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040853
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