Kynurenic Acid Levels are Increased in the CSF of Alzheimer’s Disease Patients

Kynurenic acid (KYNA) is a product of the tryptophan (TRP) metabolism via the kynurenine pathway (KP). This pathway is activated in neurodegenerative disorders, such as Alzheimer´s disease (AD). KYNA is primarily produced by astrocytes and is considered neuroprotective. Thus, altered KYNA levels may...

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Udgivet i:Biomolecules
Main Authors: González-Sánchez, Marta, Jiménez, Javier, Narváez, Arantzazu, Antequera, Desiree, Llamas-Velasco, Sara, Herrero-San Martín, Alejandro, Molina Arjona, Jose Antonio, López de Munain, Adolfo, Lleó Bisa, Alberto, Marco, M.-Pilar, Rodríguez-Núñez, Montserrat, Pérez-Martínez, David Andrés, Villarejo-Galende, Alberto, Bartolome, Fernando, Domínguez, Elena, Carro, Eva
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226436/
https://ncbi.nlm.nih.gov/pubmed/32276479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040571
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